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Full Product List

• CIA Induction Kits
• EAE Induction Kits
• Immunization Kits
• Hooke Control Kits™
• Antigens in Solution
• Tissue From Mice With CIA
• Serum From Mice With CIA
• Tissue and Cells From Mice With EAE
• Tissue From Mice With SLE
• Serum From Immunized Mice
• Control and Naive Tissue, Cells, and Serum

All current products are listed below. Click any product for details.

Most kits can be customized for a small additional charge. Contact us at or with your requirements.

CIA Induction Kits

Cat #	Hooke Kit™	Strain1	Age	Description	Size	Price (first kit)	Price (each add'l kit)
EK-0210	Chicken Collagen/CFA Emulsion	DBA/1	7 to 9 weeks	Type II collagen/CFA emulsion in syringe	20 mice	$ 427	$ 363
EK-0211	Chicken Collagen/IFA Emulsion	DBA/1	7 to 9 weeks	Type II collagen/IFA emulsion in syringe	20 mice	$ 400	$ 340
EK-0220	Bovine Collagen/CFA Emulsion	DBA/12	7 to 9 weeks	Type II collagen/CFA emulsion in syringe	20 mice	$ 427	$ 363
EK-0221	Bovine Collagen/IFA Emulsion	DBA/12	7 to 9 weeks	Type II collagen/IFA emulsion in syringe	20 mice	$ 400	$ 340

¹ Breeder substrain can substantially affect CIA development. Hooke recommends use of Taconic DBA1BO mice with these kits.

² Will also induce CIA in Lewis rats if Hooke's protocol is followed; see here.

EAE Induction Kits

(See What are the advantages and disadvantages of the different EAE models and antigens?)

C57BL/6 mice – immunization with MOG_35-55 or MOG_1-125

Cat #	Hooke Kit™	Strain	Age	Description	Size	Price (first kit)	Price (each add'l kit)
EK-2110	MOG35-55/CFA Emulsion PTX	C57BL/6	9 to 13 weeks	Emulsion in syringes, PTX	10 mice	$ 399	$ 339
EK-2160	MOG1-125/CFA Emulsion PTX	C57BL/6	9 to 13 weeks	Emulsion in syringes, PTX	10 mice	$ 2087	$ 1668

SJL mice – immunization with PLP_139-151

Cat #	Hooke Kit™	Strain	Age	Description	Size	Price (first kit)	Price (each add'l kit)
EK-0120	[Ser140]-PLP139-151/CFA Emulsion1	SJL	8 to 9 weeks	Emulsion in syringes	10 mice	$ 328	$ 279
EK-2120	[Ser140]-PLP139-151/CFA Emulsion PTX	SJL	8 to 9 weeks	Emulsion in syringes, PTX	10 mice	$ 399	$ 339
EK-0230	PLP139-151 (native)/CFA Emulsion	SJL	8 to 9 weeks	Emulsion in syringes	10 mice	$ 328	$ 279

¹ EK-0120 was called "PLP_139-151/CFA Emulsion" prior to May 2020. Only the name has changed, to avoid confusion with EK-0230.

Lewis rats – immunization with gpMBP_69-88

Cat #	Hooke Kit™	Strain	Age	Description	Size	Price (first kit)	Price (each add'l kit)
EK-3110	gpMBP69-88/CFA Emulsion	Lewis rats	9 to 14 weeks	Emulsion in syringes	10 rats	$ 358	$ 304

Additional pertussis toxin (for use with kits above)

Cat #	Product	Description	Size	SDS (pdf)	Price
BT-0105	Pertussis toxin in glycerol	PTX from B. pertussis in glycerol buffer	1 vial	SDS	$ 84

Immunization Kits

Cat #	Hooke Kit™	Strain	Description	Size	Price (first kit)	Price (each add'l kit)
EK-0111	MOG35-55/CFA Emulsion	C57BL/6 or any strain with H-2b haplotype	Emulsion in syringes	10 mice	$ 328	$ 279
EK-0120	[Ser140]-PLP139-151/CFA Emulsion1	SJL	Emulsion in syringes	10 mice	$ 328	$ 279
EK-0230	PLP139-151 (native)/CFA Emulsion	SJL	Emulsion in syringes	10 mice	$ 328	$ 279
EK-0130	MBP1-17/CFA Emulsion	B10.PL or PL/J	Emulsion in syringes	10 mice	$ 269	$ 229
EK-0132	OVA323-339/CFA Emulsion	BALB/c, D011.10 TCR transgenic, C57BL/6, OT-II TCR transgenic	Emulsion in syringes	10 to 20 mice	$ 440	$ 374
EK-0133	mBSA/CFA Emulsion	Any	Emulsion in syringes	10 to 20 mice	$ 269	$ 229
EK-0301	Ovalbumin (OVA)/CFA Emulsion	Any	Emulsion in syringes	10 to 20 mice	$ 269	$ 229
EK-0311	Ovalbumin (OVA)/IFA Emulsion	Any	Emulsion in syringes	10 to 20 mice	$ 255	$ 217

¹ EK-0120 was called "PLP_139-151/CFA Emulsion" prior to May 2020. Only the name has changed, to avoid confusion with EK-0230.

Hooke Control Kits™

Choose the Hooke Control Kit™ that corresponds to the Hooke Emulsion Kit™ to be used.

	Hooke Control Kit™		Hooke Control Kit™
Hooke Emulsion Kit™	(full size)1		(half size)2
	Cat #	Price	Cat #	Price	Description (full size kit)	SDS (pdf)
EK-0111	CK-0111	$ 246	CK-5111	$ 185	CFA emulsion	SDS
EK-0120	CK-0120	$ 246	CK-5120	$ 185	CFA emulsion	SDS
EK-0130	CK-0130	$ 202	CK-5130	$ 152	CFA emulsion	SDS
EK-0132	CK-0132	$ 202	CK-5132	$ 152	CFA emulsion	SDS
EK-0133	CK-0133	$ 202	CK-5133	$ 152	CFA emulsion	SDS
EK-0210	CK-0210	$ 156	CK-5210	$ 117	CFA emulsion	SDS
EK-0211	CK-0211	$ 151	CK-5211	$ 113	IFA emulsion	SDS
EK-0220	CK-0220	$ 156	CK-5220	$ 117	CFA emulsion	SDS
EK-0221	CK-0221	$ 151	CK-5221	$ 113	IFA emulsion	SDS
EK-0230	CK-0230	$ 246	CK-5230	$ 185	CFA emulsion	SDS
EK-0301	CK-0301	$ 202	CK-5301	$ 152	CFA emulsion	SDS
EK-0311	CK-0311	$ 191	CK-5311	$ 143	IFA emulsion	SDS
EK-2110	CK-2110	$ 299	CK-7110	$ 224	CFA emulsion, PTX in glycerol	Emulsion	PTX
EK-2120	CK-2120	$ 299	CK-7120	$ 224	CFA emulsion, PTX in glycerol	Emulsion	PTX
EK-2160	CK-2160	$ 299	CK-7160	$ 224	CFA emulsion, PTX in glycerol	Emulsion	PTX
EK-3110	CK-3110	$ 202	CK-8110	$ 152	CFA emulsion	SDS

¹ A full size kit contains the same quantity of emulsion as the corresponding Hooke Emulsion Kit™.

² A half size kit contains half that amount; suitable for smaller control groups.

Antigens in Solution

Antigens in PBS

Cat #	Product	Description	Size	SDS (pdf)	Price
DS-0142	Ovalbumin (OVA) in PBS1	Protein in PBS	2 mg in 1 mL	SDS	$ 43
DS-0162	Methylated bovine serum albumin (mBSA) in PBS	Protein in PBS	5 mg in 1 mL	SDS	$ 54

Antigens in TC media

Cat #	Product	Description	Size	SDS (pdf)	Price
DS-0111	MOG35-55 in TC media	Peptide in tissue culture media	2 mg in 1 mL	SDS	$ 165
DS-0121	[Ser140]-PLP139-151 in TC media1	Peptide in tissue culture media	2 mg in 1 mL	SDS	$ 165
DS-0131	MBP1-17 in TC media	Peptide in tissue culture media	2 mg in 1 mL	SDS	$ 165
DS-0141	OVA323-339 in TC media	Peptide in tissue culture media	2 mg in 1 mL	SDS	$ 165
DS-0151	gpMBP69-88 in TC media	Peptide in tissue culture media	2 mg in 1 mL	SDS	$ 165
DS-0161	PLP139-151 (native) in TC media	Peptide in tissue culture media	2 mg in 1 mL	SDS	$ 165

¹ DS-0121 was called "PLP_139-151 in TC media, 100x" prior to May 2020. Only the name has changed, to avoid confusion with DS-0161.

Tissue From Mice With CIA

Cat #	Strain-Gender	Disease stage	Tissue	Size	Price
CZ-0110	DBA/1-F	24-48 hours after CIA onset	Hind paw, spleen, serum	Half mouse	$ 265
CZ-0111	DBA/1-M	24-48 hours after CIA onset	Hind paw, spleen, serum	Half mouse	$ 265
CZ-0120	DBA/1-F	4-5 days after CIA onset	Hind paw, spleen, serum	Half mouse	$ 265
CZ-0121	DBA/1-M	4-5 days after CIA onset	Hind paw, spleen, serum	Half mouse	$ 265
CZ-0130	DBA/1-F	2-3 weeks after CIA onset	Hind paw, spleen, serum	Half mouse	$ 265
CZ-0131	DBA/1-M	2-3 weeks after CIA onset	Hind paw, spleen, serum	Half mouse	$ 265

(See also control and naïve tissue.)

Serum From Mice With CIA

Cat #	Strain	Antigen	Disease stage	Tissue	Size	Price
CZ-0242	DBA/1	Chicken collagen	20+ days after CIA onset	Serum	1 mL	$ 693
CZ-5242	DBA/1	Chicken collagen	20+ days after CIA onset	Serum	250 µL	$ 288
CZ-0243	DBA/1	Bovine collagen	20+ days after CIA onset	Serum	1 mL	$ 693
CZ-5243	DBA/1	Bovine collagen	20+ days after CIA onset	Serum	250 µL	$ 288

(See also control and naïve tissue.)

Tissue and Cells From Mice With EAE

Tissue from mice with EAE - snap frozen

Cat #	Strain	Disease stage	Tissue	Size	Price
EZ-1110	C57BL/6	EAE onset	Spleen & spinal cord	1 mouse	$ 307
EZ-1120	C57BL/6	EAE disease peak	Spleen & spinal cord	1 mouse	$ 307
EZ-1130	C57BL/6	EAE recovery (chronic phase)	Spleen & spinal cord	1 mouse	$ 307
EZ-1210	SJL	Onset of first wave of EAE	Spleen & spinal cord	1 mouse	$ 334
EZ-1220	SJL	Peak of first wave of EAE	Spleen & spinal cord	1 mouse	$ 334
EZ-1230	SJL	Remission from first wave of EAE	Spleen & spinal cord	1 mouse	$ 334
EZ-1240	SJL	Onset of EAE relapse (within 24 hours after onset)	Spleen & spinal cord	1 mouse	$ 438
EZ-1250	SJL	Peak of EAE relapse (2-3 days after onset)	Spleen & spinal cord	1 mouse	$ 438
EZ-1260	SJL	Recovery from EAE relapse	Spleen & spinal cord	1 mouse	$ 363

(See also control and naïve tissue.)

Cells from MOG or PLP-immunized mice - fresh

Cat #	Strain	Antigen	Product	Size	Price (first mouse)	Price (each add'l mouse)
CF-1001	C57BL/6	MOG35-55	Spleen cells	1 mouse	$ 382	$ 232
CF-1002	C57BL/6	MOG35-55	Lymph node cells	1 mouse	$ 382	$ 232
CF-1003	C57BL/6	MOG35-55	Spleen cells and lymph node cells	1 mouse	$ 448	$ 298
CF-2001	SJL	[Ser140]-PLP139-151	Spleen cells	1 mouse	$ 409	$ 259
CF-2002	SJL	[Ser140]-PLP139-151	Lymph node cells	1 mouse	$ 409	$ 259
CF-2003	SJL	[Ser140]-PLP139-151	Spleen cells and lymph node cells	1 mouse	$ 475	$ 325
CF-2231	SJL	PLP139-151 (native)	Spleen cells	1 mouse	$ 409	$ 259
CF-2232	SJL	PLP139-151 (native)	Lymph node cells	1 mouse	$ 409	$ 259
CF-2233	SJL	PLP139-151 (native)	Spleen cells and lymph node cells	1 mouse	$ 475	$ 325

(See also control and naïve tissue.)

Tissue From Mice With SLE

(NZB x NZW)F1 mice - kidney, half spleen, blood, serum

Cat #	Mouse strain	Treatment/proteinuria score	Price
LZ-0100	(NZB x NZW)F1 hybrid (NZBWF1)	Cyclophosphamide-treated (no or mild proteinuria; < 30 mg protein/dL)	$ 625
LZ-0101	(NZB x NZW)F1 hybrid (NZBWF1)	Vehicle-treated or naïve (severe proteinuria; > 500 mg protein/dL)	$ 715
LZ-0102	(NZB x NZW)F1 hybrid (NZBWF1)	Naïve, 15 to 18 weeks old (no or mild proteinuria; < 30 mg protein/dL)	$ 338

MRL/lpr mice - kidney, half spleen, blood, serum

Cat #	Mouse strain	Treatment/proteinuria score	Price
LZ-0200	MRL/lpr	Cyclophosphamide-treated (no or mild proteinuria; < 30 mg protein/dL)	$ 494
LZ-0201	MRL/lpr	Vehicle-treated or naïve (severe proteinuria; > 500 mg protein/dL)	$ 686
LZ-0202	MRL/lpr	Naïve, 6 to 8 weeks old (no or mild proteinuria; < 30 mg protein/dL)	$ 373

Serum From Immunized Mice

Cat #	Mouse strain	Immunization	Collection time	Volume	Price
IZ-1110	C57BL/6	MOG35-55/CFA	28 days from immunization	100 µL	$ 160
IZ-1240	C57BL/6	MOG1-125/CFA	28 days from immunization	100 µL	$ 275
IZ-1200	C57BL/6	Ovalbumin/CFA	14 days from immunization	100 µL	$ 160
IZ-3200	BALB/c	Ovalbumin/CFA	14 days from immunization	100 µL	$ 160
IZ-1201	C57BL/6	Ovalbumin/CFA + Ovalbumin/IFA	10 days from booster	100 µL	$ 206
IZ-3201	BALB/c	Ovalbumin/CFA + Ovalbumin/IFA	10 days from booster	100 µL	$ 206
IZ-1160	C57BL/6	mBSA/CFA	14 days from immunization	100 µL	$ 160
IZ-1161	C57BL/6	mBSA/CFA + mBSA/IFA	10 days from booster	100 µL	$ 206
IZ-3161	BALB/c	mBSA/CFA + mBSA/IFA	10 days from booster	100 µL	$ 206

See also control serum (immunized with adjuvant only) and serum from naïve (unimmunized) mice.

Control and Naive Tissue, Cells, and Serum

CIA control tissue and serum

Snap frozen tissue from mice immunized with adjuvant only (control kit; no CIA induction), matched for time from CIA induction.

Cat #	Strain-Gender	Termination	Tissue	Size	Price
CZ-0010	DBA/1-F	Time matched to 24-48 hrs after CIA onset	Hind paw, spleen, serum	Half mouse	$ 300
CZ-0011	DBA/1-M	Time matched to 24-48 hrs after CIA onset	Hind paw, spleen, serum	Half mouse	$ 300
CZ-0020	DBA/1-F	Time matched to 4-5 days after CIA onset	Hind paw, spleen, serum	Half mouse	$ 300
CZ-0021	DBA/1-M	Time matched to 4-5 days after CIA onset	Hind paw, spleen, serum	Half mouse	$ 300
CZ-0030	DBA/1-F	Time matched to 2-3 weeks after CIA onset	Hind paw, spleen, serum	Half mouse	$ 300
CZ-0031	DBA/1-M	Time matched to 2-3 weeks after CIA onset	Hind paw, spleen, serum	Half mouse	$ 300

(See also CIA tissue.)

Frozen serum from mice immunized with adjuvant only (control kit).

Cat #	Strain	Termination	Tissue	Size	Price
CZ-0270	DBA/1	35 to 60 days after immunization	Serum	1 mL	$ 828
CZ-5270	DBA/1	35 to 60 days after immunization	Serum	250 µL	$ 357

(See also CIA serum.)

EAE control tissue and cells

Snap frozen tissue from mice immunized with adjuvant only (control kit; no EAE induction), matched for time from EAE induction.

Cat #	Strain	Termination	Tissue	Size	Price
EZ-1111	C57BL/6	Time matched to EAE onset	Spleen & spinal cord	1 mouse	$ 307
EZ-1121	C57BL/6	Time matched to EAE peak	Spleen & spinal cord	1 mouse	$ 307
EZ-1131	C57BL/6	Time matched to EAE recovery	Spleen & spinal cord	1 mouse	$ 307
EZ-1211	SJL	Time matched to EAE first wave onset	Spleen & spinal cord	1 mouse	$ 334
EZ-1221	SJL	Time matched to EAE first wave peak	Spleen & spinal cord	1 mouse	$ 334
EZ-1231	SJL	Time matched to EAE first wave remission	Spleen & spinal cord	1 mouse	$ 334
EZ-1241	SJL	Time matched to EAE relapse onset	Spleen & spinal cord	1 mouse	$ 334
EZ-1251	SJL	Time matched to EAE relapse peak	Spleen & spinal cord	1 mouse	$ 334
EZ-1261	SJL	Time matched to EAE relapse recovery	Spleen & spinal cord	1 mouse	$ 334

(See also EAE tissue.)

Fresh cells from mice immunized with adjuvant only (control kit; no EAE induction). Termination at age 8 to 18 weeks.

Cat #	Strain	Antigen	Product	Size	Price (first mouse)	Price (each add'l mouse)
CF-1101	C57BL/6	CFA only	Spleen cells	1 mouse	$ 382	$ 232
CF-1102	C57BL/6	CFA only	Lymph node cells	1 mouse	$ 382	$ 232
CF-1103	C57BL/6	CFA only	Spleen cells and lymph node cells	1 mouse	$ 448	$ 298
CF-2101	SJL	CFA only	Spleen cells	1 mouse	$ 409	$ 259
CF-2102	SJL	CFA only	Lymph node cells	1 mouse	$ 409	$ 259
CF-2103	SJL	CFA only	Spleen cells and lymph node cells	1 mouse	$ 475	$ 325

Naïve tissue, cells, and serum

Snap frozen tissue from naïve mice (no immunization or disease induction).

Cat #	Strain-Gender	Termination	Tissue	Size	Price
CZ-0100	DBA/1-F	Age 8 to 18 weeks	Hind paw, spleen, serum	Half mouse	$ 114
CZ-0101	DBA/1-M	Age 8 to 18 weeks	Hind paw, spleen, serum	Half mouse	$ 108
EZ-1100	C57BL/6	Age 8 to 18 weeks	Spleen & spinal cord	1 mouse	$ 129
EZ-1200	SJL	Age 8 to 18 weeks	Spleen & spinal cord	1 mouse	$ 156

Fresh cells from naïve mice (no immunization or disease induction). Termination at age 8 to 18 weeks.

Cat #	Strain	Antigen	Product	Size	Price (first mouse)	Price (each add'l mouse)
CF-1201	C57BL/6	none	Spleen cells	1 mouse	$ 321	$ 171
CF-1202	C57BL/6	none	Lymph node cells	1 mouse	$ 321	$ 171
CF-1203	C57BL/6	none	Spleen cells and lymph node cells	1 mouse	$ 387	$ 237
CF-2201	SJL	none	Spleen cells	1 mouse	$ 348	$ 198
CF-2202	SJL	none	Lymph node cells	1 mouse	$ 348	$ 198
CF-2203	SJL	none	Spleen cells and lymph node cells	1 mouse	$ 414	$ 264

Frozen serum from naïve mice (no immunization or disease induction).

Cat #	Strain	Termination	Tissue	Size	Price
CZ-0280	DBA/1	Age 8 to 18 weeks	Serum	1 mL	$ 491
CZ-5280	DBA/1	Age 8 to 18 weeks	Serum	250 µL	$ 180
SZ-0281	C57BL/6	Age 8 to 18 weeks	Serum	1 mL	$ 478
SZ-5281	C57BL/6	Age 8 to 18 weeks	Serum	250 µL	$ 175
SZ-0283	BALB/c	Age 8 to 18 weeks	Serum	1 mL	$ 464
SZ-5283	BALB/c	Age 8 to 18 weeks	Serum	250 µL	$ 170

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Latest news

2024 Feb 16 – Anti-CD40-induced colitis model in RAG2KO mice

2024 Feb 14 – Updated protocol for EAE induction by active immunization in C57BL/6 mice

2023 Oct 29 – BTK inhibition reduces severity of secondary progressive EAE (new paper)

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