Vial photo

Pertussis toxin in glycerol

For enhancement of EAE development

Supplied in glycerol buffer

This product is for use when more severe EAE is desired. (More severe than the EAE obtained with our EAE induction kits.) For more severe EAE, increase the PTX amount by 20-50% above the dose in the recommended EAE induction protocol.

Cat # Product Description Size SDS (pdf) Price
BT-0105 Pertussis toxin in glycerol PTX from B. pertussis in glycerol buffer 1 vial SDS $ 76

Detailed contents

Pertussis toxin (PTX) from Bordetella pertussis, in glycerol buffer, 1 vial.

Each vial contains enough PTX to induce EAE in at least 10 mice.

Beacuse PTX potency varies considerably by lot, each vial contains:

Pertussis toxin: 3 to 6 µg (varies by lot)
Concentration: 0.1 to 0.2 mg/mL (varies by lot)
Total volume: 25 to 30 µL (varies by lot)

Lot-specific details (PTX amount, concentration, volume) are supplied with the product.

Turbidty: Translucent
Form: Solution
Color: None, clear

Product selection

We recommend this product as an adjuvant for EAE induction in C57BL/6 mice. This is the same PTX supplied with our EAE induction kits for C57BL/6 mice.

Storage & stability

Stable for 6 months when stored at or below -20 °C.
Administer within 2 hours of resuspension in PBS.

References

Munoz JJ et al, Cell Imunol 83:92 (1984)
Janson L et al, Eur J Immunol 21:693 (1991)
Kamradt T, et al, J Immunol 147:3296 (1991)
Mendel et al, Eur J Immunol 25:1951 (1995)

Safety Data Sheet (SDS)

Pertussis toxin in glycerol (PDF)

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