Mouse CIA Scoring
We recommend scoring CIA on the scale of 0 to 16 (0 to 4 for each paw, adding the scores for all 4 paws), using the following criteria:
| Paw score | Clinical observations |
|---|---|
| 0 | Normal paw. No obvious differences in appearance vs. healthy mice. |
| 1 | One or two toes inflamed and swollen. No apparent swelling of paw or ankle. |
| 2 | Three or more toes inflamed and swollen, but no paw swelling, OR Mild swelling of entire paw. |
| 3 | Swelling of entire paw. |
| 4 | Severe swelling of entire paw and all toes, OR Ankylosed paw and toes and the mouse cannot grip the wire top of the cage. |
CIA scoring - typical mouse paw appearance
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